Cyclopentadecanone MSDS

Production method

  1. α,ω-Hexadecanedinitrile is produced by the condensation and hydrolysis of N-Ethyl N-Phenylaminolithium in ether solution with N-Ethyl N-Phenylaminolithium as catalyst.
  2. It can be obtained from natural raw material neuronic acid by oxidation to α,ω-pentadecanedioic acid, and then reduced by esterification and cyclization to obtain cyclopentadecanone.


  1. It has been widely used in the formulation of fragrances since 50 years ago, as its aroma is softer than musk ketone, and its scenting effect is similar to that of pentadecanoide. Usually the concentration in the final product is 0.005% to 0.06% for soaps; 0.0005% to 0.006% for detergents; 0.04% to 1% for perfumes; 0.0025% to 0.01% for creams and others. In edible flavours the dosage and range is limited by its unpleasant taste with little use, drinks, candy, chewing gum and oral products with a dosage of 0.03mg/kg. also used as a solvent for sterols, carotenoids and azo dyes.
  2. Used in high grade perfume, can increase the powder and animal fragrance, can play a harmonious role with a variety of fragrance, even if added to a small amount of effect is very significant. In the daily chemical industry, it is used as a soap fragrance, detergent fragrance, perfume fragrance, cream fragrance, etc.

Cyclopentadecanone MSDS
1.1 Product identifier
: Cyclopentadecanone
Common name or trade name of the chemical
1.2 Other methods of identification
No data available
1.3 Uses and suggested unsuitable uses for the identified substance or mixture
For scientific research purposes only, not as a drug, home remedy or other use.
Module 2. Overview of hazards

2.1 GHS classification
Skin irritation (Category 3)
2.2 GHS labelling elements, including precautionary statements
Hazard type pictogram None
Signal word warning
Hazard statement
H316 causes minor skin irritation.
Warning statement
P332 + P313 If skin irritation occurs: Seek medical advice/consultation.
2.3 Other hazards – none
Module 3. Information on ingredients/ composition

3.1 Substance
: C15H28O
Molecular formula
: 224.38 g/mol
Molecular weight
CAS No. 502-72-7
EC-No. 207-951-2
Module 4. First aid measures

4.1 Description of the necessary first aid measures
General advice
Consult a doctor. Show this safety technical note to the doctor who is on site.
In case of inhalation
If inhaled, move the patient to fresh air. If breathing has stopped, give artificial respiration. Consult a doctor.
In case of skin contact
Rinse with soap and plenty of water. Consult a doctor.
In case of eye contact
Flush eyes with water as a precaution.
In case of accidental ingestion
Do not give anything from the mouth to an unconscious person. Rinse mouth with water. Consult a doctor.
4.2 Most important symptoms and effects, acute and delayed
To the best of our knowledge, the chemical, physical and toxic properties have not been fully studied.
4.3 Instructions and directions for prompt medical treatment and special treatment as required
No data available
Module 5. Fire fighting measures

5.1 Extinguishing media
Extinguishing methods and extinguishing agents
Extinguish with water spray, alcohol-resistant foam, dry powder or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
5.3 Precautions for fire-fighters
If necessary, wear self-contained breathing apparatus to fight the fire.
5.4 Further information
No data available
Module 6. Emergency response to a spill

6.1 Precautions for personnel, protective equipment and emergency procedures
Use personal protective equipment. Prevent the generation of dust. Prevent inhalation of vapours, aerosols or gases. Ensure adequate ventilation. Avoid inhalation of dust.
6.2 Environmental precautions
Do not allow products to enter sewers.
6.3 Methods and materials to contain and remove spills
Collect and dispose of spillage without creating dust. Sweep up and shovel off. Store in suitable closed disposal containers.
6.4 Refer to other sections
Refer to section 13 for disposal of discards.
Module 7. Handling Disposal and Storage

7.1 Precautions for safe handling
Provide suitable exhaust ventilation in areas where dust is generated. General fire protection measures.
7.2 Conditions for safe storage, including any incompatibilities
Store in a cool place. Keep containers tightly closed and store in a dry and ventilated place.
7.3 Specific uses
No data available
Module 8. Exposure control/individual protection

8.1 Control parameters
Maximum permissible concentration
There are no known nationally defined exposure limits.
8.2 Exposure control
Appropriate technical controls
Operate in accordance with industrial hygiene and Cyclopentadecanone supplier safe use rules. Hand washing before breaks and at the end of work.
Personal protective equipment
Eye/face protection
Safety glasses with protective edge shields in accordance with EN 166 Use equipment tested and approved by official standards such as NIOSH (USA) or EN 166 (EU) for eye protection.
Use equipment that has been tested and approved for eye protection.
Skin protection
Gloves must be checked before use.
Please remove the gloves in a suitable manner (without touching the external surface of the gloves) and avoid any skin contact with the product.
After use, dispose of contaminated gloves with care in accordance with the relevant laws and regulations and valid laboratory procedures. Wash and blow dry your hands.
The protective gloves selected must comply with the EU regulation 89/686/EEC and the EN 376 standard from which they are derived.
Body protection
The choice of body protection is based on the type, concentration and amount of the hazardous substance and the specific workplace. ,
The type of protective equipment must be selected according to the concentration and amount of the hazardous substance in the particular workplace.
Respiratory protection
Respiratory protection is not required. For protection against dust damage, use dust masks type N95 (US) or P1 (EN 143).
Use respirators and parts that have been tested and passed government standards such as NIOSH (US) or CEN (EU).
Module 9. Physical and chemical characteristics

9.1 Information on basic physical and chemical properties
a) Appearance and properties
Shape: crystalline
Colour: white
b) Odour
No data available
c) Odour threshold
No data available
d) pH value
No data available
e) Melting / freezing points
Melting point/melting point range: 63 – 65 °C – lit.
f) Starting boiling point and boiling range
120 °C at 0.4 hPa – lit.
g) Flash point
No data available
h) Evaporation rate
No data available
i) Flammability (solid, gas)
No data available
j) High/low flammability or explosivity limits No data available
k) Vapour pressure
No data available
l) Relative vapour density
No data available
m) Relative density
0.897 g/cm3 at 25 °C
n) Water solubility
No data available
o) Logarithmic value of octanol/water partition coefficient
No data available
p) Auto-ignition temperature
No data available
q) Decomposition temperature
No data available
r) Viscosity
No data available
Module 10. Stability and reactivity

10.1 Reactivity
No data available
10.2 Chemical stability
No data available
10.3 Potential for hazardous reactions
No data available
10.4 Conditions for avoiding exposure
No data available
10.5 Incompatible materials
Strong oxidising agents, strong bases, reducing agents
10.6 Hazardous decomposition products
Other decomposition products – no data available
Module 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity
No data available
Skin corrosion/irritation
Skin – Rabbits – Mild skin irritation – 24 h
Severe eye damage / eye irritation
No data available
Respiratory or skin irritation
No data available
Germ cell mutagenesis
No data available
No component of this product at levels greater than or equal to 0.1% has been identified as a probable or definite human carcinogen by the IARC.
Reproductive toxicity
No data available
Specific target organ systemic toxicity (primary exposure)
No data available
Specific target organ systemic toxicity (repeated exposure)
No data available
Inhalation hazard
No data available
Potential health effects
May be harmful if inhaled by inhalation. May cause respiratory tract irritation.
Ingestion is harmful if taken in.
Dermal May be harmful if absorbed through the skin. May cause skin irritation.
Eyes may cause eye irritation.
Signs and symptoms of exposure
To the best of our knowledge, the chemical, physical and toxic properties of this product have not been fully studied.
Additional information
Registration of toxic effects of chemical substances: GY0900000
Module 12: Ecological information

12.1 Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Potential for bioaccumulation
No data available
12.4 Transport in Soil
No data available
12.5 Evaluation of the results for PBT and vPvB
No data available
12.6 Other adverse effects
No data available
Module 13. Waste disposal

13.1 Waste disposal methods
Hand over the remaining and unrecovered solution to a disposal company. Contact a specialised waste disposal organisation with a waste disposal licence to dispose of this material.
Dissolve or mix with flammable solvents and burn in a chemical incinerator equipped for post-combustion treatment and scrubbing
Contaminated packaging
Dispose of as unused product.
Module 14. Transport information

14.1 UN number
European Land Transport Dangerous Goods: – International Maritime Transport Dangerous Goods: – International Air Transport Dangerous Goods: – International Air Transport Dangerous Goods
14.2 United Nations (UN) designations
European Dangerous Goods by Road: Non-dangerous goods
International Maritime Dangerous Goods (IMDG): Non-dangerous goods
International Air Dangerous Goods: Non-dangerous goods
14.3 Transport hazard classes
International Maritime Dangerous Goods: – International Air Dangerous Goods: –
14.4 Parcel groups
Eurocruiser: – International Maritime Dangerous Goods: – International Air Dangerous Goods: –
14.5 Environmental hazards
EC DG Land: – No DG Sea: – No DG Air: – No
14.6 Special precautions for users
No data available

Module 15 – Regulatory information


Module 16 – Other information

Toxicity and ecology of cyclopentadecanone
Toxicological data on cyclopentadecanone:

  1. Skin/eye irritation data: Standard Draize test for rabbits in direct contact with skin: 500 mg/24H
  2. Acute toxicity: Oral rat: LD50>5g/kg and dermal LD50>5g/kg. no mortality in mice at an intraperitoneal dose of 11.25mmol/kg over 24h. No mortality in 4 days at a dose of 8.92 mmol/kg. Oral doses of >45mmol/kg did not cause mortality in mice. Acute tests on mice showed no specific pathological reactions, but with increasing doses degenerative liver-like nephritis in the central ducts of the body and minimal pancreatic necrosis were observed. 3. The substance was applied to normal or damaged rabbit skin under closed conditions and showed mild irritation after 24 h. Concentrations diluted to 10% were made into petroleum jelly preparations and did not produce irritation after 48 h in closed skin contact tests in humans, and also did not produce sensitization in maximum tests in humans.
    Ecological data on cyclopentadecanone:

Generally non-hazardous to water, do not discharge into the surrounding environment without government permission.